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KMID : 1011620110270040099
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Korean Journal of Food and Cookey Science
2011 Volume.27 No. 4 p.99 ~ p.106
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Antioxidant Activity and DNA Damage Protective Effect of a Robinia pseudoacacia L. Flower Extract
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김수정:Kim Su-Jung
서고운:Seo Go-Un/서보영:Seo Bo-Young/박은주:Park Eun-Ju/이승철:Lee Seung-Cheol
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Abstract
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The antioxidant properties of Robinia pseudoacacia L. water and 70% ethanol extracts were evaluated by determining total phenolic content (TPC), DPPH radical scavenging activity (RSA), and reducing power (RP). The water extract showed higher TPC (9.07 mg/g gallic acid equivalents) and RP than those of ethanol extract, whereas ethanol extract had greater DPPH RSA. The R. pseudoacacia L. extracts also showed antigenotoxic effects for 200 μM H₂O₂-induced DNA damage in human leukocytes. The 200 μM H₂O₂-induced DNA damage decreased following treatment with the water extract. Reductions in DNA damage with 50 μg/mL of the water and ethanol extracts were 46.5 and 32.4%, respectively.
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KEYWORD
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Robinia pseudoacacia L., flower, antioxidant activity, DNA damage, antigenotoxic effect
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